This work falls within the framework of quantitatively evaluating the primary metabolites and qualitatively the secondary metabolites of the three inedible organs (bark, leaves and flowers) of the two pomegranate cultivars (Nabli and Gabsi) in order to better enhance this natural resource. . The main objective is to carry out a global study which focuses on both the study of the biochemical composition and the organoleptic study of inedible organs. The results show that protein, sugar and fatty acid composition accumulate differently depending on the cultivar. These by-products can be considered as a potential crop that could be useful in designating pomegranate by-products as an ingredient in food processing, which could provide potential health benefits. In addition, the infusions of bark, flowers and leaves have organoleptic characteristics adapted to the requirements of the panellists. We can conclude that these extracts can be used in human food.